ChoiceSpine University
These bioactive composite bone graft matrices are a combination of three components: Carbonate Apatite anorganic bovine bone mineral, 45S5 Bioactive Glass, and Type I Collagen. This trio provides a uniform distribution of bioactive glass and mineral particles throughout the matrix so that the bone graft is steadily resorbed and replaced by new bone formation.
45S5 Bioactive Glass
+ Carbonate Apatite Anorganic Bone Mineral
+ Highly-Purified, Bovine Derived Type I Collagen
Advantages of 45S5 Bioactive Glass
Favorable Environment
for bone regeneration and osteoblast attachment7.
Ion Exchange & Release
including soluble tetrahedral silica, which may promote rapid bone formation1.
Cell Proliferation & Differentiation
45S5 Bioactive glass has the ability to stimulate the growth & osteogenic differentiation of human primary osteoblasts8.
Benefits of Carbonate Apatite
• Optimal Resorption & Remodeling1, 2
• Natural Mineral Structure Similar to Human Bone Mineral
• More Calcium Phosphate Deposition Than βTCP4
• Half the crystallinity than HA, More Soluble5
• Independent Studies have shown Higher Osteoclastic & Osteoblastic Activity than βTCP & HA6
Ready to Learn More?
Item # |
Description |
Size |
| PUTTY | ||
| BA47-000002 | STRATOFUSE BA Putty | 2.5cc |
| BA47-000005 | STRATOFUSE BA Putty | 5cc |
| BA47-000010 | STRATOFUSE BA Putty | 10cc |
| BA47-000020 | STRATOFUSE BA Putty | 20cc |
| STRIPS | ||
| BA48-000005 | STRATOFUSE BA Strip | 32 x 20 x 8mm (5cc) |
| BA48-000010 | STRATOFUSE BA Strip | 62.5 x 20 x 8mm (10cc) |
| BA48-000020 | STRATOFUSE BA Strip | 125 x 20 x 8mm (20cc) |
| BA48-000040 | STRATOFUSE BA Strip | 250 x 20 x 8mm (40cc) |
Information
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Interested in Stratofuse® BA? Let us know what questions you have below.
1. Gerhardt, L., Boccaccini, A.R. (2010). Bioactive Glass-Ceramic Scaffolds for Bone Tissue Engineering. Materials, 3, 3867-3910. Retrieved from
https://doi.org/10.3390/ma3073867
2.Matsuura, A., Kubo, T., Doi K., Hayashi, K., Morita, K., Yokota, R., Hayashi, H., Hirata, I., Okazaki, M., Akagawa, Y. (2009). Bone formation ability of carbonate
apatite-collagen scaffolds with different carbonate contents. Dental Materials Journal, 28(2), 234-242.
3. Ellies, LG., Carter, J.M., Natiella, J.R., Featherstone, J.D.B., Nelson, D.G.A. (1988). Quantitative analysis of early in vivo tissue response to synthetic apatite
implants. J. of Biomed. Mater. Res., 22, 137-148.
4. In vitro data on file at Collagen Matrix, Inc.
5. Li, S.T., Chen, H.C., Yuen, D., inventors. (2011). United States patent US 8,980,328. Method of Preparing Porous Carbonate Apatite from Natural Bone.
6. Kanayama, K., Sriarj, W., Shimokawa, H., Ohya, K., Doi, Y., Shibutani, T. 2011. Osteoclast and Osteblast Activities on Carbonate Apatite Plates in Cell Cultures.
Biomaterials, 26, 435-436.
7. Hench, L.L., Polak, J.M., Xynos, I.D., Buttery, L.D.K. (2000). Bioactive Materials to Control Cell Cycle. Materials Research Innovations, 3, 313-23.
doi: 10.1007/s100190000055
8. Xynos, I.D., Hukkanen, M.V., Batten, J.J., Buttery, L.D.K, Hench, L.L., Polak, J.M. (2000). Bioglass 45S5 stimulates osteoblast turnover and enhances bone
formation In vitro: Implications and applications for bone tissue engineering. Calcif Tissue Int. 67(4), 321-9.